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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN1 All Species: 16.06
Human Site: T585 Identified Species: 27.18
UniProt: Q16512 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16512 NP_002732.3 942 103932 T585 S S P I Q E S T A P E L P S E
Chimpanzee Pan troglodytes XP_512443 1169 127241 T812 S S P L Q E S T A P E L P S E
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 F637 Y L P Q E P T F E E T P R T K
Dog Lupus familis XP_542019 1076 118222 T718 S S P I Q E T T T T P E P P S
Cat Felis silvestris
Mouse Mus musculus P70268 946 104392 T588 S S P T H E S T T S P E L P S
Rat Rattus norvegicus Q63433 946 104449 T588 S S P T H E S T T S P E L P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 S625 L E P V A G D S P C T K R P H
Chicken Gallus gallus XP_422357 1013 114806 S609 P A P P R A S S L G E I C E P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689331 948 107057 S594 Q P S T E P L S A P D V T T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 K311 N F I K V L G K G S F G K V M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 L384 D F T F M K V L G K G S F G K
Sea Urchin Strong. purpuratus XP_787090 799 90414 P445 R S S P P P S P L S Q T Q G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 H770 T F Q I E Q D H A S K E V L Q
Red Bread Mold Neurospora crassa P87253 1142 127954 A743 D A Y S S P Q A R P Q Q Q Q Q
Conservation
Percent
Protein Identity: 100 79.3 38.7 83 N.A. 91.6 91.9 N.A. 42.2 57.6 N.A. 66.7 N.A. 29 N.A. 27.8 48.5
Protein Similarity: 100 79.9 52.6 84.3 N.A. 94.7 94.6 N.A. 56.1 72.1 N.A. 79.5 N.A. 42.8 N.A. 43.4 61.7
P-Site Identity: 100 93.3 6.6 53.3 N.A. 40 40 N.A. 6.6 20 N.A. 13.3 N.A. 0 N.A. 0 13.3
P-Site Similarity: 100 100 33.3 60 N.A. 40 40 N.A. 20 46.6 N.A. 46.6 N.A. 6.6 N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.8 28.3
Protein Similarity: N.A. N.A. N.A. N.A. 44.4 45.1
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 8 8 0 8 29 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % C
% Asp: 15 0 0 0 0 0 15 0 0 0 8 0 0 0 0 % D
% Glu: 0 8 0 0 22 36 0 0 8 8 22 29 0 8 15 % E
% Phe: 0 22 0 8 0 0 0 8 0 0 8 0 8 0 0 % F
% Gly: 0 0 0 0 0 8 8 0 15 8 8 8 0 15 0 % G
% His: 0 0 0 0 15 0 0 8 0 0 0 0 0 0 8 % H
% Ile: 0 0 8 22 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 8 0 8 0 8 0 8 8 8 8 0 15 % K
% Leu: 8 8 0 8 0 8 8 8 15 0 0 15 15 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 58 15 8 29 0 8 8 29 22 8 22 29 15 % P
% Gln: 8 0 8 8 22 8 8 0 0 0 15 8 15 8 22 % Q
% Arg: 8 0 0 0 8 0 0 0 8 0 0 0 15 0 0 % R
% Ser: 36 43 15 8 8 0 43 22 0 36 0 8 0 15 22 % S
% Thr: 8 0 8 22 0 0 15 36 22 8 15 8 8 15 0 % T
% Val: 0 0 0 8 8 0 8 0 0 0 0 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _